Endometriosis is a bacterial disease: the role of fusobacteria

the reason forendometriosis or its aggravation would depend on an infection caused by bacteria in the family Fusobacterium. If this message was confirmed The treatment for this disease would be to take an antibiotic.

In our country, many women are affected by this pathology

Only in our country, between 10 and 15% of women of childbearing age suffer from this pathology. Endometriosis affects up to half of women who are infertile or have trouble conceiving. In fact, it can affect or limit your ability to get pregnant.

There are at least 3 million women with a full diagnosis. The diagnosis is one of the weak points: sometimes it only comes years later, when the situation has become particularly serious over time. This disease is represented by the presence of endometrium outside the uterus. The endometrium is the mucous membrane that lines the uterine cavity.

Data suggests that endometriosis is a bacterial disease

Researchers from Japanese universities compared data from two groups of 155 women. The results showed that 64% of women with endometriosis had an infection Fusobacterium of the endometrium compared to less than 10% of the healthy. But there is more. The working group has identified the mechanism that leads from a bacterial infection to endometriosis. This infection leads to an impaired immune response.

The researchers then tested an antibiotic in an animal model. Experts gave mice with endometriosis antibiotics. The antibiotic had the ability to prevent the development of pathology, or in any case to reduce the number and severity of lesions characteristic of the disease.

We need new insights

“Eradicating this bacterium with antibiotic treatment could be an approach to treating endometriosis in women who are positive for Fusobacteria infection.” These women could be identified with a vaginal or uterine swab.” Yutaka Kondo is the research coordinator. However, further studies are needed to confirm this hypothesis. Researchers have started human trials. The results will be available in a few months.

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